Cat. No.
MABL-086
Application
IB: IHC: IP
Isotype
Engineer antibody
Species Reactivity
Rat, Mouse
Clone No.
L6/23
From
Recombinant Antibody
Specificity
This antibody is specific for Slo1.
Alternative Names
L6/23R; Calcium-activated potassium channel subunit alpha-1; Calcium- activated potassium channel; subfamily M subunit alpha-1; KCa1.1, K(VCA)alpha; BK channel; BKCA alpha; Maxi K channel; Slo-alpha; Slowpoke homolog; Kcnma1; Kcnma,
UniProt
Q08460
Immunogen
This antibody was raised by immunising BALB/c mice with a fusion protein corresponding to the cytoplasmic C-terminus (amino acids 690-1196) of mouse Slo1.
Application Notes
The specificity of this antibody has been confirmed in western blot analysis of rat and mouse brain membrane preparations, with no bands detected in blots of brain membrane preparations from BKAlpha knockout mice (Wersinger et al, 2010). This antibody has been used in immunoblot analysis of membranes prepared from adult rat and mouse brain (Andrews et al, 2019; PMID:30667360).
Antibody First Published
Wersinger et al. BK Channels Mediate Cholinergic Inhibition of High Frequency Cochlear Hair Cells PLoS One. 2010;5(11):e13836. PMID:21079807
Note on publication
Describes the original characterisation of this antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
