Cat. No.
MABL-108
Application
ICC, WB, IHC
Isotype
Engineer antibody
Species Reactivity
Macaca fascicularis, Macaca mulatta, Rat, Human, Mouse
Clone No.
N178A/9.1
From
Recombinant Antibody
Specificity
This antibody is specific for the Cav3.1 Ca2+ channel. Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium- dependent processes
Alternative Names
N178A/9.1R; N178A/9; Voltage-dependent T-type calcium channel subunit alpha-1G; Voltage-gated calcium channel subunit alpha Cav3.1
UniProt
O54898
Immunogen
This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 2052- 2172 (cytoplasmic C-terminus) of mouse Cav3.1.
Application Notes
his antibody has been used for western blotting on proteins from the brain of mice (Calhoun et al, 2016; PMID:27112236) (Stoyas et al, 2020; PMID:31859031). Immunohistochemistry has also been preformed on the mouse brain using this antibody (Stoyas et al, 2020; PMID:31859031).
Immunohistochemistry was also preformed on the retinas of both the Rhesus macaque and the crab-eating macaque (Puthussery et al, 2013; PMID:24107939).
Antibody First Published
Puthussery et al. NaV1.1 Channels in Axon Initial Segments of Bipolar Cells Augment Input to Magnocellular Visual Pathways in the Primate Retina The Journal of Neuroscience, October 9, 2013 • 33(41):16045–16059 PMID:24107939
Note on publication
The article describes the research on initial axon segments in primate retinas
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
