Cat. No.
MABL-263
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
Species independent
Clone No.
6G1
From
Recombinant Antibody
Specificity
This antibody binds morphine and also recognizes the 6-hemisuccinyl ester of morphine. Morphine is a strong opiate that is found naturally in opium, a dark brown resin in poppies (Papaver somniferum). It is considered the classic opioid analgesic, most commonly used in pain management, morphine provides major relief to patients afflicted with pain. It is a non-synthetic narcotic with a high potential for abuse.
Alternative Names
Morphium; HSM; morphine 6-hemisuccinyl ester; opoids; ChEBI: 17303
UniProt
Immunogen
The original antibody was generated by immunizing Balb/c mice with morphine derivative, 6- hemisuccinyl ester conjugated to BSA.
Application Notes
This antibody binds morphine with a binding affinity of Kd = 123nM. The binding characterization of this antibody to the 6-hemisuccinyl ester of morphine was done using ELISA (PMID: 32219918).
Antibody First Published
Trofimov et al. Epitope specificity of two anti-morphine monoclonal antibodies: In vitro and in silico studies. J Mol Recognit. 2020 Sep;33(9):e2846. PMID:32219918
Note on publication
This paper describes the characterization of two antibodies generated against morphine.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
