Cat. No.
MABL-262
Application
RIA, ELISA
Isotype
Engineer antibody
Species Reactivity
Species independent
Clone No.
MOR158 (MOR158.1.3)
From
Recombinant Antibody
Specificity
This antibody binds morphine and cross reacts with other opioids like codeine, ethylmorphine, dihydromorphine, dihydrocodeine, dihydromorphinone, dihydrocodeinone, norcodeine, naloxone and naltrexone. Morphine is a strong opiate that is found naturally in opium, a dark brown resin in poppies (Papaver somniferum). It is considered the classic opioid analgesic, most commonly used in pain management, morphine provides major relief to patients afflicted with pain. It is a non-synthetic narcotic with a high potential for abuse.
Alternative Names
Morphium; Codeine; Ethylmorphine; Dihydromorphine; Dihydrocodeine; Dihydromorphinone; Dihydrocodeinone; Norcodeine; Naloxone; Naltrexone; ChEBI: 17303
UniProt
Immunogen
The original antibody was generated by immunizing female BALB/c mice with morphine-BSA conjugate.
Application Notes
The initial binding reactivity and cross reactivity of this antibody to morphine and other opiods was determined using ELISA and radioimmunoassay (PMID: 3211162; 8417377).
Antibody First Published
Sawada et al. Production and characterization of high-affinity monoclonal antibodies against morphine. Mol Immunol. 1988 Sep;25(9):937-43. PMID:3211162
Note on publication
Describes the generation and characterization of twelve antibodies against morphine.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
