Cat. No.
MABL-269
Application
Blocking, ELISA
Isotype
Engineer antibody
Species Reactivity
Human, Mouse
Clone No.
2C5
From
Recombinant Antibody
Specificity
The antibody is specific for amyloid precursor protein (APP). The antibody binds to human and murine APP.
Alternative Names
amyloid precursor protein; Amyloid-beta precursor protein; ABPP; APPI; Alzheimer disease amyloid A4 protein homolog; Alzheimer disease amyloid protein; Amyloid precursor protein; Amyloid-beta (A4) precursor protein; Amyloid-beta A4 protein; Cerebral vascular amyloid peptide (CVAP); PreA4; Protease nexin-II (PN-II)
UniProt
P05067
Immunogen
The antibody was generated by immunizing BALB/c mice with recombinant and active human APP-C99.
Application Notes
The specificity of the original format of the antibody for APP was confirmed by ELISA analysis. The antibody blocks the gamma-secretase-dependent processing of the amyloid precursor protein (APP) (WO2012104824A1).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
