Key features and details | |
Cat. No. | MABL-092 |
Name | Anti-Botch mAbs |
Clone No. | AFD-N116/14 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB |
Species Reactivity | Rat |
Basic Information | |
Specificity | This antibody is specific for the botch antigen in rats. This protein catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. |
Alternative Name | N116/14R; Glutathione-specific gamma-glutamylcyclotransferase 1; Gamma-GCG 1; Blocks Notch protein; Cation transport regulator-like protein 1; Neuroprotective protein 7 |
UniProt | B3STU3 |
Immunogen | This antibody was raised by immunising BALB/c mice with the botch antigen |
Application Notes | The antibody was used for western blotting on the proteins extracted from the cerebral cortex of rats (Liu et al, 2019; PMID:30646897). |
Antibody First Published | Liu et al Mesenchymal stem cells alleviate the early brain injury of subarachnoid hemorrhage partly by suppression of Notch1-dependent neuroinflammation: involvement of Botch J Neuroinflammation. 2019 Jan 15;16(1):8. PMID:30646897 |
Note on publication | Describes the use of the antibody in western blotting in the cerebral cortex of rats, after the cortex has been repaired using bone marrow stem cells. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |