Anti-GABA(A)R, Delta mAbs

Cat. No.

MABL-100

Name

Anti-GABA(A)R, Delta  mAbs

Clone No.

AFD-N151/3.3

From

Recombinant Antibody

Isotype

Engineer antibody

Application

 ICC, WB

Species Reactivity

 Rat, Mouse

Basic Information

Specificity

This antibody is specific for the   GABA(A) receptor subunit delta. GABA, the major inhibitory neurotransmitter   in the vertebrate brain, mediates neuronal inhibition by binding to the   GABA/benzodiazepine receptor and opening an integral chloride channel.

Alternative Name

N151/3.3R; N151/3;   Gamma-aminobutyric acid receptor subunit delta; GABA(A) receptor subunit   delta

UniProt

P18506

Immunogen

This antibody was raised by immunising BALB/c mice with synthetic   peptide amino acids 15- 34 (CTQPHHGARAMNDIGDYVGS, extracellular N-terminus)   of rat GABA-A-R-Delta.

Application Notes

This antibody has been used for   western blotting on the hippocampi of rats (Kharmalov et al, 2011;   PMID:21439793)

Antibody First Published

Kharmalov et al Alterations of GABA(A) and   glutamate receptor subunits and heat shock protein in rat hippocampus   following traumatic brain injury and in posttraumatic epilepsy Epilepsy Res.   2011 Jun;95(1-2):20-34. PMID:21439793

Note on publication

This article describes the   generation of a library of recombinant monoclonal antibodies (R-mAbs) from a   pool of mAb-producing hybridomas for neuroscience research.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.