Key features and details | |
Cat. No. | MABL-108 |
Name | Anti-Cav3.1 Ca2+ channel mAbs |
Clone No. | AFD-N178A/9.1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ICC, WB, IHC |
Species Reactivity | Macaca fascicularis, Macaca mulatta, Rat, Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for the Cav3.1 Ca2+ channel. Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium- dependent processes |
Alternative Name | N178A/9.1R; N178A/9; Voltage-dependent T-type calcium channel subunit alpha-1G; Voltage-gated calcium channel subunit alpha Cav3.1 |
UniProt | O54898 |
Immunogen | This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 2052- 2172 (cytoplasmic C-terminus) of mouse Cav3.1. |
Application Notes | his antibody has been used for western blotting on proteins from the brain of mice (Calhoun et al, 2016; PMID:27112236) (Stoyas et al, 2020; PMID:31859031). Immunohistochemistry has also been preformed on the mouse brain using this antibody (Stoyas et al, 2020; PMID:31859031).Immunohistochemistry was also preformed on the retinas of both the Rhesus macaque and the crab-eating macaque (Puthussery et al, 2013; PMID:24107939). |
Antibody First Published | Puthussery et al. NaV1.1 Channels in Axon Initial Segments of Bipolar Cells Augment Input to Magnocellular Visual Pathways in the Primate Retina The Journal of Neuroscience, October 9, 2013 • 33(41):16045–16059 PMID:24107939 |
Note on publication | The article describes the research on initial axon segments in primate retinas |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
