Anti-QKI-6 mAbs

Cat. No.

MABL-109

Name

Anti-QKI-6  mAbs

Clone No.

AFD-N182/17.1

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ICC, WB, IF, IHC

Species Reactivity

Human

Basic Information

Specificity

This antibody is specific for the QKI-6 protein   and shows no cross-reactivity with QKI-5, QKI-7 or QKI-7b. QKI-6 is a   RNA-binding protein that plays a central role in myelinization.

Alternative Name

N182/17.1R; N182/17; Protein quaking; Hqk;   HqkI

UniProt

Q96PU8

Immunogen

This antibody was raised by immunising   BALB/c mice with a Synthetic peptide amino acids 329-341 (PSGVLGMAFPTKG, C-terminal tail) of human QKI-6.

Application Notes

Western blot was preformed on mouse   induced pluripotent stemcells (Caines et al, 2019; PMID:31331967). This antibody has shown its use for immunofluorescense   on mouse induced pluripotent stemcells (Caines et al, 2019; PMID:31331967). Immunohistochemistry has been preformed on human carotid arteries using this antibody (de Bruin et al, 2016;   PMID:27029405). This antibody has also shown its use in western blotting on the lysate of human carotid arteries (de   Bruin et al, 2016; PMID:27029405).

Antibody First Published

de Bruin et al Quaking promotes   monocyte differentiation into proatherogenic macrophages by controlling pre-mRNA splicing and gene expression Nat Commun.   2016 Mar 31;7:10846. PMID:27029405

Note on publication

This article describes this use of this   antibody in immunological research

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.