Key features and details | |
Cat. No. | MABL-110 |
Name | Anti-QKI-5 mAbs |
Clone No. | AFD-N195A/16 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ICC, WB, IHC |
Species Reactivity | Rat, Human |
Basic Information | |
Specificity | This antibody is specific for the QKI-5 protein and shows no cross-reactivity with QKI-6, QKI-7 or QKI-7b. QKI-5 is a RNA-binding protein that plays a central role in myelinization. |
Alternative Name | N195A/16R; Protein quaking; Hqk; HqkI; N195A/16 |
UniProt | Q96PU8 |
Immunogen | This antibody was raised by immunising BALB/c mice with synthetic peptide amino acids 315- 331 (ATKVRRHDMRVHPYQRI, with nuclear localization signal underlined) of human QKI-5. |
Application Notes | Immunohistochemistry has been preformed on human carotid arteries using this antibody (de Bruin et al, 2016; PMID:27029405). This antibody has also shown its use in western blotting on the lysate of human carotid arteries (de Bruin et al, 2016; PMID:27029405). Western blot has been preformed on both human and mouse proteins using this antibody (van der Veer, 2013; PMID:23963726). |
Antibody First Published | van der Veer et al. Quaking, an RNA-Binding Protein, Is a Critical Regulator of Vascular Smooth Muscle Cell Phenotype 10/12/2013 Vol 113, Issue 9 PMID:23963726 |
Note on publication | This article describes the research on determining the role of QKI in regulating adult VSMC function and plasticity. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
