Key features and details | |
Cat. No. | MABL-160 |
Name | Anti-MESD mAbs |
Clone No. | AFD-N88/12.1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, WB, IHC |
Species Reactivity | Rat, Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for amino acids 30-95 and 118-180 (lacking VSD domain) of mouse MESD. MESD is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). |
Alternative Name | N88/12.1R; LRP chaperone MESD; Mesoderm development candidate 2; |
UniProt | Q9ERE7 |
Immunogen | This antibody was raised by immunising BALB/c mice with a fusion protein of amino acids 30- 95 and 118-180 (lacking VSD domain) of mouse MESD. |
Application Notes | This antibody is recommended for detection and analysis of MESD by immunohistochemistry, western blot or immunoprecipitation. For instance, the mouse version of this antibody was used to detect MESD by immunohistochemistry in adult rat hippocampus. |
Antibody First Published | Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360 |
Note on publication | Describes the generation of a library of recombinant monoclonal antibodies (R- mAbs) from a pool of mAb-producing hybridomas for neuroscience research. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
