Key features and details | |
Cat. No. | MABL-161 |
Name | Anti-FGF13/FHF2 mAbs |
Clone No. | AFD-N91/27.1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB |
Species Reactivity | mouse, rat, Human |
Basic Information | |
Specificity | This antibody is specific for amino acids 53-245 of human FGF13a.Cross-reacts with FGF13a and FGF13b does not cross-react with FGF11, FGF12 or FGF14 expressed in heterologous cells. FGF13a is a microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. |
Alternative Name | N91/27.1R; Fibroblast growth factor 13; FGF-13; Fibroblast growth factor homologous factor 2; FHF-2 |
UniProt | Q92913 |
Immunogen | This antibody was raised by immunising BALB/c mice with a fusion protein of amino acids 53- 245 of human FGF13a. |
Application Notes | This antibody was used for western blot analysis on mouse ventricular NaV channel protein (Burel et al, 2017; PMID:28882890). |
Antibody First Published | Burel et al. C-terminal phosphorylation of Na V 1.5 impairs FGF13- dependent regulation of channel inactivation J Biol Chem. 2017 Oct 20;292(42):17431-17448.PMID:28882890 |
Note on publication | Phosphoproteomic analyses to identify and quantify in situ the phosphorylation sites in the NaV1.5 proteins purified from adult WT and failing CaMKIIδc-overexpressing (CaMKIIδc-Tg) mouse ventricles was undertaken in this article. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
