Anti-Kvbeta1.1 K+ channel mAbs

Cat. No.

MABL-210

Name

Anti-Kvbeta1.1 K+ channel  mAbs

Clone No.

AFD-K9/40R

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, IF, IHC

Species Reactivity

Rat, Human, Mouse

Basic Information

Specificity

This antibody is specific for   Kv-beta-1. It does not cross-react with Kvβ1.2, Kvβ1.3, Kvβ2. Kv- beta-1 is a cytoplasmic potassium channel subunit that modulates the characteristics of the channel- forming alpha-subunits. Modulates action potentials via its   effect on the pore-forming alpha subunits

Alternative Name

Voltage-gated potassium channel subunit   beta-1; Kcnab1; K(+) channel subunit beta-1; Kv-beta-1; K9/40

UniProt

 P63143

Immunogen

 This antibody was raised against a synthetic   peptide of amino acids 7-28 of rat Kv1.1.

Application Notes

Immunofluorescence was preformed   using this antibody on primary hippocampal neurons from postnatal day 1   Sprague–Dawley rats (Cho et al, 2020; PMID:33168717). Primary hippocampal   neurons from postnatal day 1 Sprague–Dawley rats were used for immunohistochemistry   with this antibody (Cho et al, 2020; PMID:33168717). This antibody was used   for immunoblotting on left ventricular mouse tissue lysates (Kilfoil et al,   2019; PMID:31639389).

Antibody First Published

Andrews et al. A toolbox of IgG   subclass-switched recombinant monoclonal antibodies for enhanced multiplex   immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360

Note on publication

Describes the generation of a   library of recombinant monoclonal antibodies (R- mAbs) from a pool of   mAb-producing hybridomas for neuroscience research.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.