Key features and details | |
Cat. No. | MABL-227 |
Name | Anti-CD127 mAbs |
Clone No. | AFD-6A3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | antagonist, neutralizing, SPR, WB, ELISA, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for CD127. |
Alternative Name | IL7R; IL7Rα; IL-7Rα; Interleukin-7 receptor subunit alpha; IL-7 receptor subunit alpha; IL-7R-alpha; IL-7RA; CDw127 |
UniProt | P16871 |
Immunogen | The original antibody was generated by immunizing Balb/c mice with dimeric recombinant human CD127 extracellular domain. |
Application Notes | ELISA was performed on CD127 using this antibody (WO2010017468). This antibody was tested for inhibition of IL-7 induced IFN-γ and IL-17 in a TH17 expansion assay (WO2010017468). Flow cytometry was performed on Mock transfected CHO or CHO-CD127 cells using this antibody (WO2010017468). Surface plasmon resonance was performed with this antibody on CD127 to test the binding affinity (WO2010017468). Immunohistochemistry was performed on the spinal cord of a mouse using this antibody (WO2010017468). A neutralizing assay was performed on CD127 protein using this antibody (WO2010017468). Western blot was performed on protein extract using this antibody (WO2010017468). |
Antibody First Published | Leung et al. Treatment of autoimmune and inflammatory disease. WO2010017468 PMID: |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
