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Anti-CD39 mAbs

简要描述:

This antibody is specific for human CD39. CD39 could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.

产品参数:

Cat. No.:MABL-231

Species:Engineer

Species Reactivity:Human

Type:Recombinate

Application:FC

详细介绍

Key features and details

Cat. No.

MABL-231

Name

Anti-CD39 mAbs

Clone No.

AFD-R22

From

Recombinant Antibody

Isotype

Engineer antibody

Application

FC

Species Reactivity

Human

Basic Information

Specificity

This antibody is specific for human   CD39. CD39 could hydrolyze ATP and other nucleotides to regulate purinergic   neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and   ADP equally well.

Alternative Name

 Ectonucleoside triphosphate   diphosphohydrolase 1; ENTPD1; NTPDase 1; Ecto-ATP diphosphohydrolase 1;   Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen

UniProt

P49961

Immunogen

The mouse version of this antibody was   raised by immunizing a BALB/c rat with JY cells.

Application Notes

To study the expression and   distribution of CD39, flow cytometry was performed on PBMCs and splenic   e-cells using the mouse version of this antibody (Kansas et al, 1991;   pmid:1672348).

Antibody First Published

Kansas et al. Expression,   distribution, and biochemistry of human CD39. Role in activation-associated   homotypic adhesion of lymphocytes J Immunol. 1991 Apr 1;146(7):2235-44.   PMID:1672348

Note on publication

The distribution, biochemical   properties, and function of CD39 were characterized with the use of   antibodies.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.


 


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