Key features and details | |
Cat. No. | MABL-3161 |
Name | Anti-Type IV collagenase mAbs |
Clone No. | AFD- 3G11 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds specifically to human type IV collagenase and does not show any cross- reactivity with any other collagenases. |
Alternative Name | MMP2; Matrix Metalloprotease 2 |
UniProt | P08253 |
Immunogen | Recombinant human type IV collagenase. |
Application Notes | This antibody binds to human type IV collagenase, a metalloproteinase involved in degrading matrix proteins and hence contributing largely to metastasis in various types of cancer. |
Antibody First Published | Li et al. Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma. World Journal of Gastroenterology 2007; 11(29):4478- 4483 PMID:16052675 |
Note on publication | Describes the generation of a mouse monoclonal antibody against type IV collagenase in order to study possible routes towards colon carcinoma treatment. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
