Key features and details | |
Cat. No. | MABL-698 |
Name | Anti-CD13 mAbs |
Clone No. | AFD- 22A5 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, FC, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for CD13, with the same reactivity as MY7 and 15D6 antibodies |
Alternative Name | Alanyl Aminopeptidase; Microsomal Aminopeptidase; Aminopeptidase M; Myeloid Plasma Membrane Glycoprotein CD13; GP150; CD13; PEPN; ANPEP; APN; |
UniProt | P15144 |
Immunogen | Female BALB/c mice were primed by intraperitoneal immunization with OC-containing cell suspensions from OCL tumors. Supernatants from growth-positive cultures were screened initially for antibody on acetone-fixed OCL tumor imprints using the indirect immunofluorescent techniques. |
Application Notes | This antibody has been used for immunofluorescent staining of CD13 in human T cell lymphoma lines, observed by confocal fluorescence microscopy (Murray 1995). 22A5 may be useful for the diagnosis and immunophenotyping of leukaemia. |
Antibody First Published | Michael A. Morton, Denise Lewis, Katrina McNulty, Jean A. S. Pringle, and Tim J. Chambers Monoclonal Antibodies to Osteoclastomas (Giant Cell Bone Tumors) :Definition of Osteoclast-specific Cellular Antigens CANCER RESEARCH 45, 5663-5669, November 1985] PMID:4053038 |
Note on publication | Addresses the cellular origin of OCs, arising from a hemopoietic stem cell rather than from conventional blood cells. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
