Cat. No.
MABL-596
Application
WB, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
24H5
From
Recombinant Antibody
Specificity
The antibody is specific for calponin protein. Calponin protein is a thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. Further, the interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Alternative Names
CAP; Calponin-2; Calponin H2, smooth muscle; Neutral calponin; CGMCNO 20775
UniProt
Q99439
Immunogen
The original antibody was generated by immunizing mice with Calponin protein.
Application Notes
The antibody specifically detected Calponin beta protein in Western blot analysis. The antibody 24H5 and the commercial antibody CALP were used to stain uterine fibroids and liver tissue.Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 24H5 was higher than the commercial antibody (CN113234155A).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
