Cat. No.
MABL-854
Application
in vitro, IF
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
CBL 562 (204.12)
From
Recombinant Antibody
Specificity
This antibody is specific for CD28.
Alternative Names
TP44; T-cell-specific surface glycoprotein CD28; 204.12
UniProt
P10747
Immunogen
The original antibody was raised by immunizing a mouse with CD28.
Application Notes
The original version of this antibody was used to activate purified human peripheral blood leucocytes (Sandilands et al., 2010; PMID:20964641). The original version of this antibody was also used for immunofluorescence staining on frozen biopsy sections from vastus lateralis or tibialis anterior muscle (Fasth et al., 2009; PMID:19752224).
Antibody First Published
Fasth et al. T cell infiltrates in the muscles of patients with dermatomyositis and polymyositis are dominated by CD28null T cells J Immunol. 2009 Oct 1;183(7):4792-9. PMID:19752224
Note on publication
The original paper aims to characterize T cells in muscle tissue and circulation and to investigate their association to clinical phenotype.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
