Cat. No.
MABL-870
Application
FC, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
UCHT1
From
Recombinant Antibody
Specificity
Epitopes on CD3-ε found in heterodimers with CD3-δ and with CD3-γ of α/β T cell receptor (TCR).
Alternative Names
CD3e; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3-ε;
UniProt
P07766
Immunogen
Human infant thymocytes.
Application Notes
This antibody binds to murine CD3 epsilon. It partially cross-blocks binding of clone 500A2 (Ab00212) indicating that overlapping epitopes are detected by these antibodies.
Antibody First Published
Beverley PC, Callard RE. Distinctive functional characteristics of human "T" lymphocytes defined by E rosetting or a monoclonal anti-T cell antibody. Eur J Immunol. 1981 Apr;11(4):-329:34. PMID:6788570
Note on publication
Describes the generation of the antibody, shows it recognised human T lymphocytes using flow cytometry and functional assays.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
