Cat. No.
MABL-1340
Application
IHC
Isotype
Engineer antibody
Species Reactivity
Zebrafish, Human
Clone No.
RCK108
From
Recombinant Antibody
Specificity
The antibody is specific for Cytokeratin 19. Cytokeratin 19 is found in most simple epithelia and non keratinized squamous epithelia with predominant focal reactivity.
Alternative Names
K19; CK-19; Keratin type I cytoskeletal 19; Cytokeratin-19; Keratin-19
UniProt
P08727
Immunogen
The original antibody was generated by immunizing mice with cell line T24.
Application Notes
The antibody could be used as a broad epithelial marker for carcinoma detection, due to its reproducible and highly sensitive staining. The antibody stained practically all epithelial tumours, especially adenocarcinoma, but it is negative in hepatocellular carcinoma (Kwaspen et al., 1997; PMID: 9447381). Antibody RCK108 reacts with a 40 kDa keratin (Cytokeratin 19) in immunoblot.
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
