Cat. No.
MABL-1353
Application
Latex and RBC Agglutination, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
3B6
From
Recombinant Antibody
Specificity
Recognises epitopes that reside between amino acids 86 and 302 in the gamma-chain of fragment D chains of fibrinogen (Fragment D) and other cross-linked fibrin degradation products containing D-Dimer, but no reactivity with Fragment D or E, fibrinogen or fibrinogen degradation products.
Alternative Names
XDP; Fragment D-dimer; Fibrin degradation fragment; Fibrin degradation product
UniProt
P02671
Immunogen
Human cross-linked D-Dimer.
Application Notes
Antibody First Published
Bundesen P.G and Rylatt D. B. Monoclonal antibodies with specificity for crosslinked fibrin derivatives and assay for said derivatives. (1988) Patent US 4758524 A
Note on publication
Murine monoclonal antibody 3B6 (also DD-3B6/22) was disclosed in patent (US4758524 A). The antibody is specific for D-Dimer and represents the first clot-specific antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
