Cat. No.
MABL-1370
Application
WB, ELISA, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
14G1C12
From
Recombinant Antibody
Specificity
The antibody is specific for Desim. Desim is a muscle-specific type III intermediate filament essential for proper muscular structure and function. It plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity.
Alternative Names
UniProt
P17661
Immunogen
The original antibody was generated by immunizing BALB/c mice with recombinant DESMIN.
Application Notes
This antibody was used for immunohistochemistry on esophageal, leiomyoma and rhabdomyosarcoma tissue (CN109485724).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
