Cat. No.
MABL-1547
Application
Blocking, WB, ELISA
Isotype
Engineer antibody
Species Reactivity
Neisseria meningitidis
Clone No.
JAR5
From
Recombinant Antibody
Specificity
This antibody binds to FHbp with a Kd of 54 pM.
Alternative Names
FHbp
UniProt
C6KHT4
Immunogen
Genome-derived neisserial Antigen 1870.
Application Notes
This antibody binds to N. meningitidis FHbp, a virulence factor critical for surviving of the bacteria in the human host. This antibody shows strong inhibition of human FH binding.
Antibody First Published
Welsch et al. Protective activity of monoclonal antibodies to genome-derived neisserial antigen 1870, a Neisseria meningitidis candidate vaccine. Journal of Immunology 2004; 172(9):5606-5615 PMID:15100304
Note on publication
Describes the generation of several antibodies against eneisserial antigen 1870 and study of their passive protection against bacteremia.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
