Cat. No.
MABL-1645
Application
therapeutic, WB, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
2E 12
From
Recombinant Antibody
Specificity
This antibody is specific for human Gal-9.
Alternative Names
Galectin-9; Gal-9; LGALS9; Ecalectin; Tumor antigen HOM-HD-21
UniProt
O00182
Immunogen
The original antibody was generated by immunizing BALB/c mice with a recombinant c- terminus galectin-9 (residues 191 to 355 of the galectin-9 long isoform).
Application Notes
The binding of the original format of this antibody to c-terminus Gal-9 was assessed via ELISA. This antibody detected Gal-9 in a WB assay (Barjon et al., 2012; PMID: 22805533). An scFv-CAR version of this antibody with therapeutic potential was developed and described (US20230295564A1).
Antibody First Published
Barjon et al. A novel monoclonal antibody for detection of galectin-9 in tissue sections: application to human tissues infected by oncogenic viruses. Infect Agent Cancer. 2012 Jul 17;7(1):16. PMID:22805533
Note on publication
The original publication presents the development of monoclonal antibodies targeting galectin-9.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
