Key features and details | |
Cat. No. | MABL-916 |
Name | Anti-CD39 mAbs |
Clone No. | AFD- I-392 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | neutralize, ELISA, FC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody recognizes and binds human CD39. NTPDase 1 (ectonucleoside triphosphate diphosphohydrolase, also known as CD39/ENTPD1 or vascular CD39, functions together with another enzyme, CD73 (ecto-5'- nucleosidase), to hydrolyze extracellular adenosine triphosphate (ATP) and adenosine diphosphate (ADP) to generate adenosine, which binds to adenosine receptors and inhibits T-cell and natural killer (NK)-cell responses, thereby suppressing the immune system. This protein could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. |
Alternative Name | ENTPD1; NTPDase 1; Ectonucleoside triphosphate Di phosphohydrolase 1; Ecto-ATP Di phosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen |
UniProt | P49961 |
Immunogen | |
Application Notes | |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
