Cat. No.
MABL-1764
Application
Blocking, WB, ELISA
Isotype
Engineer antibody
Species Reactivity
Influenza A
Clone No.
IF1A11
From
Recombinant Antibody
Specificity
The antibody binds to Influenza A H3N2 with a Kd of 3.6 nM.
Alternative Names
Hemagglutinin; HA
UniProt
P03437
Immunogen
RNA from peripheral blood lymphocytes of a healthy volunteer who had recovered from an Influenza A virus infection.
Application Notes
The antibody binds to H3N2, which binds to sialic acid-containing receptor on the host cell surface leading to attachment and internalization of the virion. The antibody neutralizes the H3N2- receptor interaction.
Antibody First Published
Shibuya et al. Identification of a human monoclonal Fab with neutralizing activity against H3N2 influenza A strain from a newly constrctued human Fab library. Microbiology and Immunology 2008; 52(3):162-170 PMID:18402598
Note on publication
Describes the generation of a Fab library and a H3N2-neutralizing antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
