Cat. No.
MABL-1782
Application
Cristallization
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
Fv3468
From
Recombinant Antibody
Specificity
The antibody is specific for subunit beta of hCG. The antibody interacts with the loop 73B-81B of subunit beta.
Alternative Names
hCG; CGB; Human chorionic gonadotropin; Choriogonadotropin subunit beta; Chorionic gonadotropin chain beta; CG-beta
UniProt
P0DN86
Immunogen
The scFv fragment was derived from hybridoma cells secreting the monoclonal antibody designated 3468.
Application Notes
The crystal structure of the antibody in complex with hCG subunit beta was determined (Tegoni et al., 1999; PMID: 10373373).
Antibody First Published
Tegoni et al. Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits. J Mol Biol. 1999 Jun 25;289(5):1375-85. PMID:10373373
Note on publication
The original paper describes the generation and characterization of the antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
