Cat. No.
MABL-1901
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
MAK33
From
Recombinant Antibody
Specificity
The antibody binds specifically to the human creatine-kinase-MM subtype (and not the the MB or BB subtype).
Alternative Names
CK-MM
UniProt
P06732
Immunogen
Human creatine-kinase-MM in Al(OH)3.
Application Notes
This antibody binds to human muscle creatine-kinase-MM, an enzyme that catalyzes the conversion of creatine and ATP to phosphocreatine and ADP, generating an ATP-buffer in the muscle. The antibody blocks CK-MM activity by 80%.
Antibody First Published
Buckel et al. Cloning and nucleotide sequence of heavy- and light-chain cDNAs from a creatine-kinase specific monoclonal antibody Gene 1987; 51:13-19 PMID:3110009
Note on publication
Describes the generation of a monoclonal antibody directed against the human creatine kinase M-subunit.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
