Cat. No.
MABL-1947
Application
FACS, WB, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
IgD26
From
Recombinant Antibody
Specificity
This antibody recognises human IgD which is a main antigen receptor on the surface of immature B-cells and small amount of it is secreted to the blood serum. On B-cells it takes part in the activation of these lymphocytes.
Alternative Names
immunoglobulin D; immunoglobulin heavy constant delta; Igh-5; Ighd; immunoglobulin Delta
UniProt
P01880
Immunogen
This antibody was raised by immunising mice with IgD purified from human myeloma serum.
Application Notes
IgD26 may be used as a primary or secondary antibody. For instance, one group used anti-IgD antibody to label IgD in a cryostat tonsil section in the immunoperoxidase staining (Naiem et al., 1982).
Antibody First Published
Taylor and Mason The immunohistological detection of intracellular immunoglobulin in formalin-paraffin sections from multiple myeloma and related conditions using the immunoperoxidase technique. Clin Exp Immunol. 1974 Nov;18(3):417-29. PMID:4219910
Note on publication
This article describes the earliest application of this antibody present in the literature. The more detailed desription of the generation of such antibodies is described in the following paper: Naiem, M., Gerdes, J., Abdulaziz, Z., Sunderland, C. A., Allington, M. J., Stein, H., & Mason, D. Y. (1982). The value of immunohistological screening in the production of monoclonal antibodies. Journal of immunological methods, 50(2), 145-160.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
