Cat. No.
MABL-2238
Application
FC, IHC-Fr
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
2G3
From
Recombinant Antibody
Specificity
This antibody binds to the ectodomain of Langerin (CD207).
Alternative Names
CD207; C-type lectin domain family 4 member K; CLC4K
UniProt
Q9UJ71
Immunogen
Human Langerin ectodomain fused to human IgFc
Application Notes
This antibody can be used to identify Langerin-positive dendritic cells. This antibody has also been used to specifically target vaccine-peptides to dendritic cells.
Antibody First Published
Igyártó et al. Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses. Immunity. 2011 Aug 26;35(2):260-72. PMID:21782478
Note on publication
Describes the generation of the antibody and use in identifying Langerin-positive cells.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
