Cat. No.
MABL-2239
Application
FC, IHC-Fr
Isotype
Engineer antibody
Species Reactivity
Pig, Human, Cynomolgus Monkey, Mouse
Clone No.
4C7
From
Recombinant Antibody
Specificity
This antibody binds to the ectodomain of Langerin (CD207).
Alternative Names
CD207; C-type lectin domain family 4 member K; CLC4K
UniProt
Q9UJ71
Immunogen
Langerin ectodomain fused to human IgFc
Application Notes
This antibody can be used to identify Langerin-positive dendritic cells. This antibody has also been used to specifically target vaccine-peptides to dendritic cells.
Antibody First Published
Flamar et al. Noncovalent assembly of anti-dendritic cell antibodies and antigens for evoking immune responses in vitro and in vivo. J Immunol. 2012 Sep 1;189(5):2645-55. PMID:22865916
Note on publication
Describes the use of 4C7 in targeting vaccine antigens to dendritic cells.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
