Cat. No.
MABL-2241
Application
ELISA, IF, IHC
Isotype
Engineer antibody
Species Reactivity
Human, Mouse
Clone No.
2F10
From
Recombinant Antibody
Specificity
This antibody is specific for an evolutionally conserved unique sequence (10 amino acids) located in LAP and mature TGF-β1 regions of latent TGF-β1 polypeptide.
Alternative Names
LAP; latent TGF-β1; Transforming growth factor beta-1-binding protein 1; LTBP-1; Latent-transforming growth factor beta-binding protein 1; TGF-beta1-BP-1
UniProt
Q14766
Immunogen
The original antibody was raised by immunizing mice with evolutionally conserved unique sequences (10 amino acids) located in LAP and mature TGF-βΙ regions of latent TGF-βΙ polypeptide.
Application Notes
Immunohistochemistry was performed against a cancer tissue array (including 6 HCC clones, 6 choiangiocarcinoma clones, 6 lung adenocarcinoma clones, 6 RCC clones, 5 breast cancer clones, 6 ovarian cancer clones, 2 cervix cancer clones) using this antibody (WO2018235964). Immunofluorescense was performed against a HepG2 cells using this antibody (WO2018235964). ELISA with this antibody was performed on antigen peptide and TGF- i (WO2018235964). This antibody was also used for immunostaining on colorectal cancer tissues (WO2019045086).
Antibody First Published
Yukikazu et al. Anti-tgf-beta1 antibodies. WO2018235964
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
