Cat. No.
MABL-2325
Application
crystallization, SPR, ELISA
Isotype
Engineer antibody
Species Reactivity
Species independent
Clone No.
1H7
From
Recombinant Antibody
Specificity
The antibody specifically binds to mannopyranosid.
Alternative Names
alpha-D-mannopyranoside
UniProt
Immunogen
The original antibody was generated by immunizing BALB/c mice against mannopyranoside- KLH.
Application Notes
The specificity of the original format of the antibody was confirmed by ELISA analysis. The binding affinity of the original format of the antibody to mannopyranoside was measured by surface plasmon resonance (Kd= 0.17 μM) (Goel et al., 2004; PMID: 15585860). The crystal structure of the Fab format of the antibody was determined by XRD (PMID: 18032557).
Antibody First Published
Goel et al., Plasticity within the antigen-combining site may manifest as molecular mimicry in the humoral immune response. J Immunol. 2004 Dec 15;173(12):7358-67. doi: 10.4049/jimmunol.173.12.7358. PMID:15585860
Note on publication
The original paper describes the generation and characterization of the antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
