Cat. No.
MABL-2422
Application
FC, IHC
Isotype
Engineer antibody
Species Reactivity
Human, Cynomolgus Monkey
Clone No.
AbAb-MUC17
From
Recombinant Antibody
Specificity
This antibody specifically recognizes the membrane bound human and cynomolgus monkey mucin-17, which is a membrane-bound mucin that provides protection to gut epithelial cells from carcinogenic effects of chronic inflammation. It is also indicated that mucin-17 is highly expressed in gastric cancer specimens and is a compelling target for prognosis of gastric cancer.
Alternative Names
MUC17; MUC-17; MUC3; MUC-3; Small intestinal mucin-3
UniProt
Q685J3
Immunogen
The original antibody was generated by immunizing B6 mice with whole CHO cells transiently expressing huMUC17.
Application Notes
This antibody can be used for the detection of surface bound human MUC17 using flow cytometry. This antibody is recommended for staining formalin-fixed paraffin-embedded human and cynomolgus monkey tissues using immunohistochemistry (WO2021188851).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.