Cat. No.
MABL-2445
Application
plate test
Isotype
Engineer antibody
Species Reactivity
Bothrops asper (Terciopelo)
Clone No.
TPL0039_05_E2
From
Recombinant Antibody
Specificity
TPL0039_05_E2 antibody recognizes myotoxin-II, which is one of the major toxins in the venom of the snake Bothrops asper (Terciopelo).
Alternative Names
Basic phospholipase A2 homolog 2; svPLA2 homolog; Myotoxin-II; MtxII
UniProt
P24605
Immunogen
In order to raise the antibody, three phage display selection rounds were performed against myotoxin-II, using the IONTAS library. The IONTAS library is a human antibody phage display library of 4 x 10^10 clones displaying antibodies in the short chain variable fragment (scFv) form.
Application Notes
TPL0039_05_E2 scFv (and its other antibody formats) is recommended for the research on anti-myotoxin-II (Bothrops asper (Terciopelo)) treatment (for snakebites).
Antibody First Published
Sørensen et al. Discovery of human recombinant antibodies against myotoxin-II from the notorious Bothrops asper. 10.13140/RG.2.2.35413.47847.
Note on publication
This poster describes the generation and characterization of the TPL0039_05_E2 antibody, as a potential treatment for Bothrops asper snakebites.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
