Cat. No.
MABL-2496
Application
WB, IF
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
10F10-C6-C6
From
Recombinant Antibody
Specificity
The antibody reacts with NORE1A epitope located within amino acids 119-191 of the human NORE1A protein, a unique sequence in the NORE1A splice form.
Alternative Names
Ras association domain-containing protein 5; New ras effector 1; Regulator for cell adhesion and polarization enriched in lymphoid tissues; RAPL
UniProt
Q8WWW0
Immunogen
The original antibody was generated by immunizing mice against amino acids 119-416 of human NORE1A.
Application Notes
This antibody has been used to specifically bind NORE1A in Western blots (Kuznetsov et al, 2008; pmid:19098985); it detected NORE1A in human HBEC3-KT cells (Moshnikova et al, 2006; pmid:16421102). Immunofluorescence was performed on human bronchial epithelial cells (HBEC3-KT or HBEC3-KTR) using this antibody (Moshnikova et al, 2006; pmid:16421102).
Antibody First Published
Moshnikova et al. The growth and tumor suppressor NORE1A is a cytoskeletal protein that suppresses growth by inhibition of the ERK pathway J Biol Chem. 2006 Mar 24;281(12):8143-52. PMID:16421102
Note on publication
The article describes the generation and characterization of the antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.