Cat. No.
MABL-2539
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
3910
From
Recombinant Antibody
Specificity
The antibody binds to E3G with an affinity of 1.43 nM.
Alternative Names
E3G
UniProt
Immunogen
Human E3G.
Application Notes
The antibody is specific for Oestrone-3-glucuronide (E3G), a urinary metabolite of 17β- estradiol, a hormone secreted by the developing ovarian follicles. The monoclonal antibodies can be used clinically to detect levels of E3G in urine samples of women, providing a non-invasive test for determining the fertile period, indicating the time of ovulation.
Antibody First Published
He M, Gani M, Livnah O, Stura EA, Beale D, Coley J, Wilson IA, Taussig MJ. Sequence, specificity and crystallization of an oestrone-3-glucuronide antibody (3910). Immunology. 1997 Apr;90(4):632-9. PMID:9176119
Note on publication
Describes the generation of the monoclonal antibody 3910, specific for oestrone-3- glucuronide (E3G). The antibody has neutralising activity, and its crystal structure allows us to determine the binding interactions between 3910 and its ligand,
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
