Cat. No.
MABL-2602
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
panfilovirus
Clone No.
4B3B5
From
Recombinant Antibody
Specificity
The antibody is specific for glycoproteins (GP). In particular, it targets the epitope GAFFLYDRLAST (a.k.a peptide 1), that is conserved across all ebolavirus and marburgvirus spp glycoproteins (GP)
Alternative Names
GP1,2; GP; filovirus; filovirus Gp; Envelope glycoprotein; Virion spike glycoprotein
UniProt
Q66810; P35253
Immunogen
The original antibody was generated by immunizing BALB/c mice with the conserved B cell epitope of filovirus Gp.
Application Notes
The specificity of the original format of the antibody was confirmed by ELISA analysis (Bongcam-Rudloff et al. 2023).
Antibody First Published
Bongcam-Rudloff et al. Consensus DNA and amino acids sequences of the recombinant panfilovirus glycoprotein specific mAb 4B3B5 and its expression in CHO mammalian cell lines Preprint from Research Square, 01 Feb 2023. DOI: PPR610922 10.21203/rs.3.rs-2532962/v1 PPR:
Note on publication
The paper describes the generation and characterization of the antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
