Cat. No.
MABL-2641
Application
functional assay, Block, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
PD1-28
From
Recombinant Antibody
Specificity
This antibody is specific for PD-1.
Alternative Names
CD279; Programmed cell death protein 1; PDCD1; PD-1; hPD-1
UniProt
Q15116
Immunogen
The original antibody was generated by panning against an scFv phagemid library generated from non-immunized human donors.
Application Notes
An ELISA was performed on PD-1 fusion protein using this antibody (US7488802). This antibody was capable of blocking the PD-1/PD-L1 interaction. It was found that PD1-28 can mimic PD-1 ligands and deliver an inhibitory signal causing a decrease in T cell proliferation and IL-2 production (US7488802).
Antibody First Published
Collins et al. Antibodies against PD-1. US7488802
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
