Cat. No.
MABL-2684
Application
IP, ELISA, IF
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
rGL-7
From
Recombinant Antibody
Specificity
This antibody binds specifically to PhGlc.
Alternative Names
PhGlc
UniProt
Immunogen
Human Peripheral Lymphocates (HPL).
Application Notes
This antibody binds to phosphatidylglucoside, a glyco-glycerophospholipid which is involved in the signalling leading to granulocyte differentiation. The antibody stimulates rapid tyrosine phosphorylation of the Src-family protein kinases Lyn and Hck.
Antibody First Published
Natasuka et al. Carbohydrate-dependent signaling from the phosphatidylglocisde-based microdomain induces granulocytic differentiation of HL60 cells. Proceedings of the National Academy of Sciences 2003; 100(13):7454-7459 PMID:12802014
Note on publication
Describes the identification of a glycolipid component in granulocytic signalling leading to CD38 expression.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
