Cat. No.
MABL-2698
Application
in vitro, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
PV-Ab1
From
Recombinant Antibody
Specificity
This antibody is specific for human PIKVA-II.
Alternative Names
Protein induced by vitamin K deficiency-II; protein induced by vitamin K absence-II; abnormal prothrombin glycoprotein
UniProt
Immunogen
The original antibody was generated by immunizing BALB/c mice with a polypeptide sequence based on the 11th-26th amino acid sequence of PIVKA-II. This region specifically lacked γ- carboxylation, which helped distinguish it from normal thrombin. An additional 8 amino acid sequence was added to enhance immunogenicity. The immunogen was coupled to KLH using EDC as a crosslinker.
Application Notes
The original antibody's specificity was validated via an ELISA. This antibody was successfully used as part of a chemiluminescent detection kit for PIKVA-II, with a detection limit of 1.38 mAU/mL (CN112175925A).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
