Cat. No.
MABL-2765
Application
FC, IF, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
8C5
From
Recombinant Antibody
Specificity
This antibody recognizes protocadherin FAT2 which is involved in the regulation of cell migration.
Alternative Names
Protocadherin Fat 2; FAT 2; hFat2; Cadherin family member 8; Multiple epidermal growth factor-like domains protein 1; Multiple EGF-like domains protein 1; Fat 2
UniProt
Q9NYQ8
Immunogen
The original mouse IgG1 version of this antibody was raised by immunizing mice with a purified recombinant human FAT2 fusion protein.
Application Notes
This antibody is recommended for the detection and analysis of protocadherin FAT2. It was used to detect and visualize protocadherin FAT2 via immunohistochemistry in formalin fixed, paraffin- embedded tissues, such as human urothelial cancer and human cervical carcinoma.
Antibody First Published
Chen and Gumbiner Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activity J Cell Biol. 2006 Jul 17;174(2)；301-13. doi: 10.1083/jcb.200602062. PMID:16847104
Note on publication
This article describes the anti-protocadherin antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
