Cat. No.
MABL-2909
Application
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
Siglec7-01
From
Recombinant Antibody
Specificity
This antibody binds human siglec-7. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid.
Alternative Names
CD328; SIGLEC7; AIRM1; AIRM-1; SIGL7; CDw328; D-siglec; p75; Sialic acid-binding Ig-like lectin 7; Adhesion inhibitory receptor molecule 1; QA79 membrane protein
UniProt
Q9Y286
Immunogen
The original antibody was isolated from a human Fab antibody library by panning against human siglec-7.
Application Notes
This antibody can bind recombinant human siglec-7 protein in an ELISA and western blot. The binding affinity of the IgG antibody for human siglec-7 was reported to be Kd= 71.5 nM. In vitro, this antibody was capable of enhancing killing effect of NK cells on tumor cells (CN106831989).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
