Cat. No.
MABL-2916
Application
IP, ELISA, FC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
OX117
From
Recombinant Antibody
Specificity
This antibody binds to human SIRP-beta and gamma.
Alternative Names
CD172b/g; Human Signal Regulatory Protein gamma; Human Signal Regulatory Protein beta
UniProt
Q9P1W8
Immunogen
Recombinant human SIRPγ:CD4 fusion protein.
Application Notes
This antibody binds to human Signal-regulatory protein gamma, an immunoglobulin- like cell surface receptor binding CD47. It mediates cell-cell adhesion and enhances T-cell activation.
Antibody First Published
Brooke et al. Human lymphocytes interact directly with CD47 through a novel member of the signal regulatory protein (SIRP) family. Journal of Immunology 2004; 173(4):2562-2570 PMID:15294972
Note on publication
Describes the identification of a new member of the SIRP-family and its interaction with CD47 as well as the generation of a monoclonal antibody against it.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
