Cat. No.
MABL-3025
Application
Biacore, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
H7
From
Recombinant Antibody
Specificity
This antibody bind to human Tenascin C.
Alternative Names
TNC; TN-C,
UniProt
P24821
Immunogen
2D-PAGE gel isolated human Tenascin C from lysate of human melanoma COLO-38 cells.
Application Notes
Tenascin C interacts with a wide range of proteins, in particular integrins and fibronectins. These interactions modify cell adhesion and influence cell migration as well as metalloproteinase expression.
Antibody First Published
Pini et al. Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel. J Biol Chem. 1998 Aug 21;273(34):21769-76. PMID:9705314
Note on publication
Describes generation, using phage display, of antibodies with subnanomolar affinity against markers of angiogenesis.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
