Cat. No.
MABL-3112
Application
antagonist, ELISA
Isotype
Engineer antibody
Species Reactivity
Rat
Clone No.
52-1H4 e2
From
Recombinant Antibody
Specificity
This antibody binds rat toll like receptor 4.
Alternative Names
CD284; Tlr4; Toll-like receptor 4; Toll4; TLR4/MD2
UniProt
Q9QX05
Immunogen
Application Notes
This antibody was reported to completely inhibit lipopolysaccharide-induced interleukin-6 secretion in vitro. The binding of this antibody to rat cells stable expressing TLR4/MD2 was done using ELISA (PMID: 33290148).
Antibody First Published
Sato et al. Generation and characterization of a novel anti-rat TLR4/MD2 antibody with potent neutralizing activity in vivo. Monoclon Antib Immunodiagn Immunother. 2020 Dec;39(6):217-221. PMID:33290148
Note on publication
Describes the generation and characterization of rat TLR4/MD2 antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
