Cat. No.
MABL-3130
Application
WB, Block, ELISA, FC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
TW4.20
From
Recombinant Antibody
Specificity
Binds to the N-terminal domain of human transferrin.
Alternative Names
Serotransferrin
UniProt
Q06AH7
Immunogen
Iron-free purified human transferrin.
Application Notes
This antibody recognises transferrin a protein which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. This antibody can displace transferrin from the transferrin receptor.
Antibody First Published
Orlandini et al. Cloning, characterization, and modeling of a monoclonal anti- human transferrin antibody that competes with the transferrin receptor Protein Sci. 3 (9), 1476-1484 (1994) PMID:7530542
Note on publication
Describes the generation and characterisation of this antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
