Key features and details | |
Cat. No. | MABL-1058 |
Name | Anti-CD62L mAbs |
Clone No. | AFD- MEL-14 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, Block, FC, IHC |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody binds to mouse CD62L the mouse peripheral lymph node homing receptor, which is a lectin-like cell surface protein rapidly down-regulated upon cell activation with phorbol 12-myristate 13- acetate. |
Alternative Name | L-selectin; LECAM-1; Ly-22; MEL14; Leu-8 |
UniProt | P18337 |
Immunogen | C3H/eb mouse B lymphoma 38C-13. |
Application Notes | This antibody detects mouse CD62L and has been reported to inhibit the interaction of neutrophils with endothelial cells in vitro and inhibit the migration of neutrophils from the blood into sites of acute inflammation in the skin (Lewinsohn et al. 1987). |
Antibody First Published | Lewinsohn, Bargatze & Butcher Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes. J Immunol. 1987 Jun 15;138(12):4313-21. PMID:3584977 |
Note on publication | Describes the generation of this. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
