Cat. No.
MABL-3161
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
3G11
From
Recombinant Antibody
Specificity
This antibody binds specifically to human type IV collagenase and does not show any cross- reactivity with any other collagenases.
Alternative Names
MMP2; Matrix Metalloprotease 2
UniProt
P08253
Immunogen
Recombinant human type IV collagenase.
Application Notes
This antibody binds to human type IV collagenase, a metalloproteinase involved in degrading matrix proteins and hence contributing largely to metastasis in various types of cancer.
Antibody First Published
Li et al. Antitumor activity of anti-type IV collagenase monoclonal antibody and its lidamycin conjugate against colon carcinoma. World Journal of Gastroenterology 2007; 11(29):4478- 4483 PMID:16052675
Note on publication
Describes the generation of a mouse monoclonal antibody against type IV collagenase in order to study possible routes towards colon carcinoma treatment.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
